Bagrat Shainyan | Chemistry | Best Researcher Award

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Prof. Bagrat Shainyan | chemistry | Best Researcher Award

 Professor at Irkutsk Institute of Chemistry, Siberian Branch of Russ. Ac. Sci., Russia

Bagrat A. Shainyan is a distinguished Professor of Chemistry at the Irkutsk Institute of Chemistry. Born in Latvia in 1949, he has established a notable career in organic and physical organic chemistry, contributing significantly to the field through extensive research and international collaboration.

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Shainyan has authored numerous publications and has been an influential figure in the academic community. His research output is widely cited, reflecting his contributions to the advancement of organic chemistry.

Education

Shainyan graduated from Leningrad (St.-Petersburg) State University and received his Ph.D. in organic chemistry in 1977. He further advanced his qualifications with a Doctor of Chemistry degree in 1988.

Research Focus

His research has predominantly focused on nucleophilic vinylic substitution, the chemistry of triflates, heterocyclic compounds, organosilicon chemistry, and organofluorine compounds. His work encompasses synthesis, structural studies, theoretical calculations, and conformational analysis.

Professional Journey

Shainyan began his career with a research focus on nucleophilic vinylic substitution. In 1992, he expanded his expertise through a year-long collaboration at the Hebrew University of Jerusalem with Professor Zvi Rappoport. By 1994, he became the Head of the Laboratory of Asymmetric Reactions, which evolved into the Laboratory of Organofluorine Chemistry in 2001, and later into the Laboratory of Organoelement Compounds in 2016.

Collaborations and Projects

Throughout his career, Shainyan has received numerous accolades for his contributions to chemistry. His research and leadership have been recognized both within Russia and internationally.

Research Timeline

  • 1977: Received Ph.D. in organic chemistry.
  • 1988: Achieved Doctor of Chemistry degree.
  • 1992: Conducted research at the Hebrew University of Jerusalem.
  • 1994: Appointed Head of Laboratory of Asymmetric Reactions.
  • 2001: Laboratory renamed to Laboratory of Organofluorine Chemistry.
  • 2016: Laboratory renamed to Laboratory of Organoelement Compounds.

Collaborations and Projects

Shainyan has collaborated extensively with international researchers and institutions, participating in numerous conferences across Europe, the Americas, Japan, and China. His collaborative projects have significantly advanced the understanding of organic and physical organic chemistry. His current work continues in the field of organoelement compounds, reflecting the legacy of the late Academician M.G. Voronkov.

Publications
    1. The Reactions of Alkenes with Phenyl-N-triflylimino-λ³-iodane: Solvent and Oxidant Impact
      International Journal of Molecular Sciences
      2023-11
      DOI: 10.3390/ijms242115947
      Contributors: Mikhail Moskalik, Anton S. Ganin, Bagrat Shainyan
    2. Gas-Phase Structure of 3,7,9-tris(trifluoromethylsulfonyl)-3,7,9-triazabicyclo[3.3.1]nonane by GED and Theoretical Calculations
      Molecules
      2023-05
      DOI: 10.3390/molecules28093933
      Contributors: Bagrat Shainyan, Alexey Eroshin, Valeria Mukhina, Sergey A. Shlykov
    3. 2-Amino-1,3-benzothiazole: Endo N-Alkylation with α-Iodo Methyl Ketones Followed by Cyclization
      Molecules
      2023-02
      DOI: 10.3390/molecules28052093
      Contributors: Ivan A. Dorofeev, Larisa V. Zhilitskaya, Nina O. Yarosh, Bagrat Shainyan
    4. Conjugative Stabilization versus Anchimeric Assistance in Carbocations
      Molecules
      2022-12
      DOI: 10.3390/molecules28010038
      Contributors: Bagrat Shainyan
    5. Triflamidation of Allyl-Containing Substances: Unusual Dehydrobromination vs. Intramolecular Heterocyclization
      Molecules
      2022-10
      DOI: 10.3390/molecules27206910
      Contributors: Anton S. Ganin, Mikhail Moskalik, Ivan A. Garagan, Vera V. Astakhova, Bagrat Shainyan

Strength for Best Researcher Award

    1. Innovative Research Contributions
      Bagrat A. Shainyan’s research has led to significant advancements in organic and physical organic chemistry. His work on nucleophilic vinylic substitution and organoelement compounds has been both pioneering and influential, earning him recognition in the academic community.
    2. Extensive Collaboration
      Shainyan’s extensive international collaborations with leading researchers and institutions highlight his ability to work effectively within the global scientific community. His collaborative projects have advanced the field and showcased his expertise on a global scale.
    3. Diverse Research Focus
      His research spans several key areas in chemistry, including organofluorine chemistry, organosilicon chemistry, and heterocyclic compounds. This breadth demonstrates his versatility and deep understanding of various subfields.
    4. High-Impact Publications
      Shainyan has authored numerous high-impact publications in reputable journals such as International Journal of Molecular Sciences and Molecules. His work is widely cited, reflecting its significance and influence in the field.
    5. Leadership and Innovation
      His leadership roles, particularly in evolving laboratories such as the Laboratory of Organofluorine Chemistry and the Laboratory of Organoelement Compounds, illustrate his ability to drive innovation and research excellence.

    Areas for Improvement

    1. Broader Outreach and Dissemination
      While Shainyan has an impressive publication record, enhancing outreach through diverse media and platforms could further disseminate his research findings and increase their impact beyond traditional academic circles.
    2. Increased Engagement in Emerging Fields
      Expanding his research into emerging areas such as green chemistry and sustainable practices could address contemporary challenges and position his work at the forefront of new scientific trends.
    3. Enhanced Public Communication
      Improving communication of his research to the general public and stakeholders outside of academia could raise awareness of the relevance and impact of his work, fostering broader support and interest.
    4. Strengthening Interdisciplinary Collaborations
      Greater emphasis on interdisciplinary collaborations could lead to novel insights and applications, bridging gaps between chemistry and other scientific disciplines.
    5. Securing Additional Funding
      Increasing efforts to secure funding from diverse sources could support more extensive and ambitious research projects, further advancing his contributions to the field.

    Conclusion

    Bagrat A. Shainyan’s distinguished career in organic and physical organic chemistry reflects his innovative research, extensive international collaborations, and leadership in evolving scientific fields. His contributions, evidenced by high-impact publications and influential roles in laboratory development, underscore his prominence as a researcher. To further enhance his impact, Shainyan could focus on broader outreach, engagement in emerging fields, public communication, interdisciplinary collaborations, and securing additional funding. By addressing these areas, he can continue to advance the field of chemistry and extend his influence both within and beyond the academic community.

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Jiyeon Han | Matrix composites | Best Researcher Award

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Assist Prof Dr. Jiyeon Han | Bioinorganic chemistry | Best Researcher Award

 Professor at University of Seoul , South Korea

Dr. Jiyeon Han is an Assistant Professor in the Department of Applied Chemistry at the University of Seoul. Her research delves into the intricate roles of metals, amyloid-β, and neuropeptides in Alzheimer’s Disease, leveraging both molecular-level studies and chemical tool development to explore and address neurodegenerative processes.

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Dr. Han has a substantial publication record with 25 articles to her name, including notable journals like Nature Chemistry, Accounts of Chemical Research, and Proceedings of the National Academy of Sciences. Her work has earned several front cover features and high-impact citations.

Education

Dr. Han earned her B.S. and M.S. from Ulsan National Institute of Science and Technology (UNIST), followed by her Ph.D. and postdoctoral training at Korea Advanced Institute of Science and Technology (KAIST) under Professor Mi Hee Lim.

Research Focus

Her primary research focuses on the molecular interactions of metals and amyloid-β in Alzheimer’s Disease, including the development of novel chemical tools to target and analyze pathogenic elements and the mechanisms of metal-induced neurodegeneration.

Professional Journey

Dr. Han transitioned from a postdoctoral scholar at KAIST to her current role at the University of Seoul in September 2022. Her career trajectory highlights her commitment to advancing the field of bioinorganic chemistry and neurodegenerative disease research.

Honors & Awards

She has received several prestigious awards, including the S-Oil Best Ph.D. Thesis Award, the 2022 Future Talent Award, and the Best Ph.D. Thesis Award from the Korean Chemical Society, recognizing her exceptional contributions to the field.

Publications Noted & Contributions

Her notable publications include studies on copper trafficking systems, the impact of metal ions on amyloid-β, and mechanistic insights into Alzheimer’s Disease. Her work has been highlighted in prominent journals and featured on front covers.

Research Timeline

Dr. Han’s research timeline includes significant milestones such as her postdoctoral fellowship in 2022, the receipt of various awards throughout 2022 and 2023, and her ongoing contributions to bioinorganic chemistry through her current faculty position.

Collaborations and Projects

Her collaborative projects span across various institutions and involve extensive work with KAIST, UNIST, and other Korean universities, focusing on metal ion interactions, chemical tool development, and neurodegenerative disease mechanisms.

 

Publications

  1. Colorimetric Detection of Fe3+ and Fe2+ and Sequential Fluorescent Detection of Al3+ and Pyrophosphate by an Imidazole-Based Chemosensor in a Near-Perfect Aqueous Solution
    TG Jo, KH Bok, J Han, MH Lim, C Kim
    Dyes and Pigments 139, 136-147 (2017)
    Cited by: 96
  2. Regulatory Activities of Dopamine and Its Derivatives Toward Metal-Free and Metal-Induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer’s Disease
    E Nam, JS Derrick, S Lee, J Kang, J Han, SJC Lee, SW Chung, MH Lim
    ACS Chemical Neuroscience 9 (11), 2655-2666 (2018)
    Cited by: 84
  3. Structure-Mechanism-Based Engineering of Chemical Regulators Targeting Distinct Pathological Factors in Alzheimer’s Disease
    MW Beck, JS Derrick, RA Kerr, SB Oh, WJ Cho, SJC Lee, Y Ji, J Han, …
    Nature Communications 7 (1), 13115 (2016)
    Cited by: 83
  4. Link of Impaired Metal Ion Homeostasis to Mitochondrial Dysfunction in Neurons
    E Nam, J Han, JM Suh, Y Yi, MH Lim
    Current Opinion in Chemical Biology 43, 8-14 (2018)
    Cited by: 72
  5. A Novel “Off-On” Type Fluorescent Chemosensor for Detection of Zn2+ and Its Zinc Complex for “On-Off” Fluorescent Sensing of Sulfide in Aqueous Solution, In Vitro and In Vivo
    JM Jung, JH Kang, J Han, H Lee, MH Lim, KT Kim, C Kim
    Sensors and Actuators B: Chemical 267, 58-69 (2018)
    Cited by: 63

Strength for Best Researcher Award

      1. High-Impact Publications
        Dr. Han’s research has been featured in top-tier journals like Nature Communications and ACS Chemical Neuroscience, demonstrating significant contributions to the field of bioinorganic chemistry and neurodegenerative diseases.
      2. Innovative Research Focus
        Her work on the molecular roles of metals and amyloid-β in Alzheimer’s Disease showcases a novel approach to understanding and targeting neurodegenerative processes.
      3. Awards and Recognition
        Dr. Han has received several prestigious awards, including the S-Oil Best Ph.D. Thesis Award and the Best Ph.D. Thesis Award from the Korean Chemical Society, underscoring her excellence in research.
      4. Collaborative Efforts
        Her extensive collaborations with institutions like KAIST and UNIST highlight her ability to work across different research environments, enhancing the impact and reach of her studies.
      5. Substantial Citations
        Her key publications have been highly cited, reflecting the broad recognition and influence of her research in the academic community.

      Areas for Improvement

      1. Broader Research Topics
        Expanding research to include a wider range of neurodegenerative diseases could enhance the applicability of her findings.
      2. Interdisciplinary Approaches
        Integrating insights from other fields such as computational biology or systems biology might provide a more comprehensive understanding of Alzheimer’s Disease mechanisms.
      3. Increased Funding Opportunities
        Securing additional funding could support larger-scale studies and the development of new chemical tools.
      4. Enhanced Public Engagement
        Greater efforts in communicating her research to the public and engaging in outreach activities could increase awareness of her work and its implications.
      5. Long-Term Research Impact
        Focusing on longitudinal studies could help track the long-term effects of her research findings on Alzheimer’s Disease and related areas.

      Conclusion

      Dr. Jiyeon Han’s achievements as an assistant professor in the Department of Applied Chemistry at the University of Seoul are marked by her groundbreaking research on the roles of metals and amyloid-β in Alzheimer’s Disease. Her high-impact publications, prestigious awards, and successful collaborations underscore her contributions to bioinorganic chemistry. However, there are opportunities for growth in expanding research topics, employing interdisciplinary approaches, securing more funding, enhancing public engagement, and focusing on long-term research impact. Addressing these areas could further elevate her research profile and broader influence in the scientific community.

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